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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMPS
All Species:
22.42
Human Site:
S473
Identified Species:
54.81
UniProt:
P49915
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49915
NP_003866.1
693
76715
S473
L
K
I
V
A
D
F
S
A
S
V
K
K
P
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105046
693
76701
S473
L
K
I
V
A
D
F
S
A
S
V
K
K
P
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3THK7
693
76705
S473
L
K
I
V
A
D
F
S
A
S
V
K
K
P
H
Rat
Rattus norvegicus
Q4V7C6
693
76739
S473
L
K
I
V
A
D
F
S
A
S
V
K
K
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512299
631
69806
K416
D
F
S
A
S
V
K
K
P
H
T
L
L
Q
R
Chicken
Gallus gallus
NP_001006556
693
76616
S473
L
K
I
V
A
D
F
S
A
S
V
K
K
P
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956881
692
76917
S472
L
K
I
I
T
D
F
S
A
S
V
K
K
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_620114
683
76772
K462
I
R
V
I
V
D
Y
K
N
K
L
Q
K
N
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09580
792
88052
Q561
N
S
A
I
N
P
S
Q
G
I
Y
E
H
L
Q
Sea Urchin
Strong. purpuratus
XP_783757
684
75195
A463
L
R
L
L
V
N
Y
A
E
S
M
D
K
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
N.A.
N.A.
97.9
97.9
N.A.
87.7
94.5
N.A.
86.8
N.A.
58
N.A.
46.3
64.9
Protein Similarity:
100
N.A.
100
N.A.
N.A.
99.2
99.1
N.A.
90.7
98.2
N.A.
94.6
N.A.
75.1
N.A.
61.3
80.9
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
0
100
N.A.
86.6
N.A.
20
N.A.
0
33.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
6.6
100
N.A.
93.3
N.A.
66.6
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
50
0
0
10
60
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
70
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
60
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
80
% H
% Ile:
10
0
60
30
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
60
0
0
0
0
10
20
0
10
0
60
80
0
0
% K
% Leu:
70
0
10
10
0
0
0
0
0
0
10
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
10
0
0
0
0
70
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
10
% Q
% Arg:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
10
0
10
0
10
60
0
70
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
10
50
20
10
0
0
0
0
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _